I think unblinding would have particularly affected the ivermectin placebo arm, and not the other placebo arms, because residents of Brazil know exactly what ivermectin is supposed to look like, since it’s available over the counter. And they can also go out and get their own IVM. The trial papers do not claim to have dosed identical placebo pills, only identical bottles, and there was no order placed for identical placebo pills with the sole possible provider in Brazil, nor permission to import.
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TOGETHER Trial: Solving the 3-Day Placebo Subgroup Riddle
I think unblinding would have particularly affected the ivermectin placebo arm, and not the other placebo arms, because residents of Brazil know exactly what ivermectin is supposed to look like, since it’s available over the counter. And they can also go out and get their own IVM. The trial papers do not claim to have dosed identical placebo pills, only identical bottles, and there was no order placed for identical placebo pills with the sole possible provider in Brazil, nor permission to import.